Please use this identifier to cite or link to this item: http://ktisis.cut.ac.cy/handle/10488/10005
Title: A review on cylindrospermopsin: The global occurrence, detection, toxicity and degradation of a potent cyanotoxin
Authors: De La Cruz, Armah A. 
Hiskia, Anastasia 
Kaloudis, Triantafyllos 
Chernoff, Neil 
Hill, Donna 
Antoniou, Maria G. 
He, Xuexiang 
Loftin, Keith 
O'Shea, Kevin 
Zhao, Cen 
Pelaez, Miguel 
Han, Changseok 
Lynch, Trevor J. 
Dionysiou, Dionysios D. 
Keywords: Chemistry
Environmental Sciences
Issue Date: 1-Nov-2013
Publisher: Royal Society of Chemistry
Source: Environmental Science Processes and Impacts, 2013, Volume 15, Issue 11, Pages 1979-2003
Abstract: Cylindrospermopsin is an important cyanobacterial toxin found in water bodies worldwide. The ever-increasing and global occurrence of massive and prolonged blooms of cylindrospermopsin-producing cyanobacteria poses a potential threat to both human and ecosystem health. Its toxicity is associated with metabolic activation and may involve mechanisms that adversely affect a wide variety of targets in an organism. Cylindrospermopsin has been shown to be cytotoxic, dermatotoxic, genotoxic, hepatotoxic in vivo, developmentally toxic, and may be carcinogenic. Human exposure may occur through drinking water, during recreational activities and by consuming foods in which the toxin may have bioaccumulated. Drinking water shortages of sufficient quality coupled with growing human pressures and climate variability and change necessitate an integrated and sustainable water management program. This review presents an overview of the importance of cylindrospermopsin, its detection, toxicity, worldwide distribution, and lastly, its chemical and biological degradation and removal by natural processes and drinking water treatment processes. © 2013 The Royal Society of Chemistry.
URI: http://ktisis.cut.ac.cy/handle/10488/10005
ISSN: 2050-7887
Rights: © Royal Society of Chemistry 2017
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